Children with MS have been shown to have a significantly increased likelihood, relative to healthy age-matched peers, of being previously infected with Epstein-Barr virus (EBV) (Alotaibi et al., 2004). EBV infection leads to persistent B-cell infection, and B-cells are known to play a role in MS. Study of children enrolled   more »

Multiple sclerosis (MS) in children is being recognized with increasing frequency. The first descriptions of MS in children were published by Charcot between 1829 and 1849, though it was not for another 50 years that MS in children was again described in the literature (Hanefeld, 2007). There are now several national programs focused   more »

Researchers at The Hospital for Sick Children (SickKids), Toronto, Canada have shown an association between paediatric multiple sclerosis (MS) and the Epstein-Barr virus (EBV), indicating that exposure to the virus at a certain time in childhood may be an important   more »