Johns Hopkins scientists have discovered to their surprise that nerves in the mammalian brain’s white matter do more than just ferry information between different brain regions, but in fact process information the way gray matter    more »

Oregon Health & Science University neuroscientist researchers, working with colleagues at the Portland Veterans Affairs Medical Center and the University of Padova in Italy, have shown that genetically inactivating a protein called cyclophilin D can protect nerve    more »

A steady rise in autoimmune diseases such as multiple sclerosis (MS) has been noted in recent decades, and environmental factors could be the cause of this increase. One theory, similar to the "hygiene hypothesis" in which an excessively germ-free environment may contribute to    more »

The aim of the study was to evaluate the frequency of edema of the lower limbs in multiple sclerosis (MS) patients utilizing a multidisciplinary approach.    more »

Autoimmune mechanisms are thought to have a major role in the pathogenesis of multiple sclerosis. We aimed to identify coexisting autoimmune phenotypes in patients with multiple sclerosis from families with several members with the disease and   more »

A natural substance made from soy appears to have amazing restorative powers when given to animals with a multiple sclerosis (MS)-like disease   more »

Natural history studies provide important information on the prognosis of multiple sclerosis and on risk factors for long-term outcome and thus help orientate treatment decisions and design clinical trials. Before the introduction of disease-modifying treatment, large longitudinal natural    more »

MBP8298 is currently being evaluated in two pivotal Phase III clinical trials in secondary progressive MS (SPMS) and one Phase II trial in relapsing-remitting MS (RRMS). BioMS will    more »

Treosulfan (L-threitol-1,4-bis(methanesulfonate)) is a bifunctional alkylating agent with a favourable profile of side effects, approved for the treatment of ovarian cancer. Treosulfan has previously been shown to reduce the severity   more »

In multiple sclerosis (MS), the myelin that surrounds the axons of nerve cells is attacked by the body’s own T cells, resulting in slowed and disrupted    more »

Results of a study suggest that people with mild to moderate multiple sclerosis (MS) are capable of improving their aerobic fitness levels similar to their non-MS counterparts. While physical inactivity may    more »

natalizumab results in significant improvements in scores on health-related quality of life (QoL) questionnaires in patients    more »

The past few years have witnessed major advancements in our ability to diagnose multiple sclerosis (MS) and begin treatments that can favourably modify the course of the disease. In addition, there is now a much better understanding of the pathogenesis of the disease and an increasing interest in “decoding” the    more »

Among individuals with MS, the extent of mental and physical functioning appears to be affected by the sociodemographic factors, such as education level, and the severity of MS, a study published    more »

A new study of twins suggests that living farther north of the equator significantly increases risk of developing Multiple Sclerosis (MS) among those with genetic    more »