Patients with relapsing-remitting multiple sclerosis (RRMS) who receive glatiramer acetate (GA) or interferon (IFN) beta show a reduction in cognitive impairment and relative stability of cognitive and affective variables at 2 years, according to the results of an observational study presented   more »

Initial results from the one-year Phase III TRANSFORMS study show the investigational oral compound FTY720 (fingolimod) has superior efficacy to a current standard of care for patients with relapsing-remitting multiple sclerosis (MS). Patients on oral FTY720 experienced significantly fewer relapses than those treated with   more »

The goal of the current study was to evaluate the effect of intramuscular interferon beta-1a therapy on long-term disability and quality-of-life outcomes in patients who had completed 2 or more years of the MSCRG trial, said Robert Bermel, MD, Mellen Center   more »

The study examined the implications of responsibility and obligation on separation-individuation processes and the appearance of various symptoms of psychological distress in    more »

Whether a patient has poor health or good health can affect his or her behaviours relating to physicians, taking prescription drugs, sources of health information and trust in health care    more »

Johns Hopkins scientists have discovered to their surprise that nerves in the mammalian brain’s white matter do more than just ferry information between different brain regions, but in fact process information the way gray matter    more »

Oregon Health & Science University neuroscientist researchers, working with colleagues at the Portland Veterans Affairs Medical Center and the University of Padova in Italy, have shown that genetically inactivating a protein called cyclophilin D can protect nerve    more »

A steady rise in autoimmune diseases such as multiple sclerosis (MS) has been noted in recent decades, and environmental factors could be the cause of this increase. One theory, similar to the "hygiene hypothesis" in which an excessively germ-free environment may contribute to    more »

The aim of the study was to evaluate the frequency of edema of the lower limbs in multiple sclerosis (MS) patients utilizing a multidisciplinary approach.    more »

Autoimmune mechanisms are thought to have a major role in the pathogenesis of multiple sclerosis. We aimed to identify coexisting autoimmune phenotypes in patients with multiple sclerosis from families with several members with the disease and   more »

A natural substance made from soy appears to have amazing restorative powers when given to animals with a multiple sclerosis (MS)-like disease   more »

Natural history studies provide important information on the prognosis of multiple sclerosis and on risk factors for long-term outcome and thus help orientate treatment decisions and design clinical trials. Before the introduction of disease-modifying treatment, large longitudinal natural    more »

MBP8298 is currently being evaluated in two pivotal Phase III clinical trials in secondary progressive MS (SPMS) and one Phase II trial in relapsing-remitting MS (RRMS). BioMS will    more »

Treosulfan (L-threitol-1,4-bis(methanesulfonate)) is a bifunctional alkylating agent with a favourable profile of side effects, approved for the treatment of ovarian cancer. Treosulfan has previously been shown to reduce the severity   more »

In multiple sclerosis (MS), the myelin that surrounds the axons of nerve cells is attacked by the body’s own T cells, resulting in slowed and disrupted    more »