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View Article  Study - Clustering of autoimmune diseases in families with a high-risk for MS
Autoimmune mechanisms are thought to have a major role in the pathogenesis of multiple sclerosis. We aimed to identify coexisting autoimmune phenotypes in patients with multiple sclerosis from families with several members with the disease and   more »
View Article  soy-based substance might help fight MS
A natural substance made from soy appears to have amazing restorative powers when given to animals with a multiple sclerosis (MS)-like disease   more »
View Article  importance of long-term data in multiple sclerosis
Natural history studies provide important information on the prognosis of multiple sclerosis and on risk factors for long-term outcome and thus help orientate treatment decisions and design clinical trials. Before the introduction of disease-modifying treatment, large longitudinal natural    more »
View Article  Eli Lilly and BioMS Medical's multiple sclerosis drug MBP8298.
MBP8298 is currently being evaluated in two pivotal Phase III clinical trials in secondary progressive MS (SPMS) and one Phase II trial in relapsing-remitting MS (RRMS). BioMS will    more »
View Article  Treatment of active secondary progressive multiple sclerosis (SPMS) with Treosulfan
Treosulfan (L-threitol-1,4-bis(methanesulfonate)) is a bifunctional alkylating agent with a favourable profile of side effects, approved for the treatment of ovarian cancer. Treosulfan has previously been shown to reduce the severity   more »
View Article  Which T cell types drive the autoimmune response in multiple sclerosis?
In multiple sclerosis (MS), the myelin that surrounds the axons of nerve cells is attacked by the body’s own T cells, resulting in slowed and disrupted    more »
View Article  Exercise Can Cut Coronary Artery Disease Risk For Some With Multiple Sclerosis
Results of a study suggest that people with mild to moderate multiple sclerosis (MS) are capable of improving their aerobic fitness levels similar to their non-MS counterparts. While physical inactivity may    more »
View Article  Natalizumab Has Benefits on Disability
natalizumab results in significant improvements in scores on health-related quality of life (QoL) questionnaires in patients    more »
View Article  New Insights and Trends
The past few years have witnessed major advancements in our ability to diagnose multiple sclerosis (MS) and begin treatments that can favourably modify the course of the disease. In addition, there is now a much better understanding of the pathogenesis of the disease and an increasing interest in “decoding” the    more »
View Article  Disease Severity, Sociodemographic Factors May Influence Mental Function, Motor Function Among Patients With MS
Among individuals with MS, the extent of mental and physical functioning appears to be affected by the sociodemographic factors, such as education level, and the severity of MS, a study published    more »
View Article  MS in Genetically Susceptible Twins
A new study of twins suggests that living farther north of the equator significantly increases risk of developing Multiple Sclerosis (MS) among those with genetic    more »