Gabapentin is, primarily, an anticonvulsant drug used, most often, in the treatment of epileptic seizures, although it has been shown to relieve spasticity and painful muscle spasm in MS.   more »

The American Academy of Neurology (AAN) is one of many medical groups that believe the use of human embryonic stem cells in biomedical research may have enormous potential to   more »

Stem cells are cells that can renew themselves over long periods by division and have the capacity to develop into individual or different cell types with specific characteristics (differentiation). Under suitable conditions   more »

Researchers demonstrate both genetic and pharmaceutical evidence for the role of a protein called collagenase-2 in the development of multiple sclerosis (MS), providing a potential new way to   more »

Inflammation-induced oxidative stress can lead to axonal degeneration, which is felt to be a major determinant of progressive neurological disability in Multiple Sclerosis (MS).   more »

The researchers studied an aspect of MS called Uhthoff's phenomenon, named for the German ophthalmologist who reported in 1889 that some people have temporary vision problems after exercise or in hot weather. This   more »

An international panel met in Washington, DC, recently under the auspices of the National MS Society’s International Advisory Committee on Clinical Trials in MS to discuss the ethics of conducting placebo-controlled trials in multiple sclerosis. This has become of increasing concern now   more »

Regulatory T cells, which function like immune system police, learn early in life what to protect, and that may include viruses, bacteria, and tumours,   more »

Immune cells called T lymphocytes recognize invaders in the body, such as viruses, bacteria, tumour cells, or allergens. Normally, T cells are activated by a complex series of    more »

The Phase I single ascending dose, double blind placebo controlled randomized study involved 56 healthy volunteers who received the drug in   more »

OBJECTIVE : To determine if task performance and fatigability during rapid repetitive exercise of the lower limb differ in a group of MS subjects compared to a control group, and what central changes accompany   more »

This study was concerned with examining relation between anxiety, depression, and locus of control (LC) in Croatian multiple sclerosis (MS) patients in order to   more »

A relationship between the latitude related distribution of multiple sclerosis (MS) and exposure to sunlight has long been considered. Higher sun exposure during early   more »

To estimate the age- and sex-specific incidence rate and lifetime risk of multiple sclerosis, we identified all new cases of MS during the period 1993-2000 in the General   more »

A steady rise in autoimmune diseases such as multiple sclerosis (MS) has been noted in recent decades, and environmental factors could be the cause of this increase. One theory, similar to the "hygiene hypothesis" in which an excessively germ-free environment may contribute to    more »