Serono (drt-x: SEO and NYSE: SRA) announced today that recruitment in the U.S. is beginning for the Phase III CLARITY study (CLAdRIbine Tablets in Treating MS OrallY Study) of oral cladribine for the treatment of patients with relapsing forms of multiple sclerosis (MS). This multi-national study was successfully   more »

Recent study outcomes suggest that among women with multiple sclerosis, the age of the first menstrual cycle may be associated with the age a woman experiences the first symptoms of MS. To evaluate the affect of hormone changes during a first menstrual cycle on MS risk, the investigators sent a survey to 438 female patients with relapsing-remitting MS living in the provinces of Newfoundland and Labrador. Participants were asked   more »

Multiple Sclerosis is an inflammatory disease of the central nervous system (CNS) that damages the insulating material that surrounds the nerve fibers in the brain, spinal cord, and nerves of the   more »

The function of upper body extremities appears to be related to cognitive function and disability level among patients with multiple sclerosis, a new study indicates. The study authors sought to evaluate the relationship between hand and arm function with cognitive function, disability and fatigue among MS patients. A total of 31 patients with   more »

Inflammatory multiple sclerosis (MS) lesions are characterized by microglia activation and infiltration of T cells, B cells, and macrophages across the blood-brain barrier (BBB). In the experimental autoimmune    more »

Chromos Molecular Systems, Inc., (CHR) has signed a contract with AppTec Laboratory Services, Inc., (AppTec) for scale-up and manufacture of its monoclonal antibody drug product candidate CHR-1103. Chromos has used its   more »

According to findings from a Danish study, having brothers and sisters does not appear to raise the risk of MS in younger siblings. Some researchers have suggested that developing an infection at a certain age during childhood may increase the risk of developing MS, the authors explained. To evaluate this theory, investigators studied   more »

Recent study findings indicate that symptoms of overactive bladder syndrome appear to have more impact on the quality of life of women with MS than women without MS. Symptoms of overactive bladder include   more »

An editorial accompanying a published debate on the pros and cons of starting treatment early in the course of multiple sclerosis comes down in favour of early treatment for this potentially devastating disease. This opinion coincides with a consensus paper published by the National MS Society. The April issue of the Archives of Neurology features both sides of this debate on   more »

The first therapy that I will discuss is Glatiramer Acetate (Copaxone), because I have been asked a question about that therapy. Later I will write about the other therapies   more »

Taking a course in energy conservation can significantly help MS patients avoid feelings of fatigue, according to data from a study published in the October issue of the journal Multiple Sclerosis. The study, which included 169 participants with MS   more »

Pregnant women with MS who deliver vaginally may have more complicated labors than women without MS, a new study indicates. Researchers sought to evaluate the effect of MS on infant deliveries and birth outcomes among women who did not plan to undergo caesarean   more »

New study findings suggest that patients with MS appear to experience a decline in mental functioning during the early stage of the disease. To assess mental or cognitive impairments in the early stage of MS, researchers compared 21 MS patients with 22 subjects without MS. The patients with MS had experienced their first neurological symptom within   more »

Socio-economic status may play role in differences of disability related to multiple sclerosis between black patients with MS and white patients with MS, a recent study finds. In the trial, investigators sought to compare the differences in MS-related disability among 21,557 white and black patients with MS. All participants were   more »

A new Danish study suggests that patients with multiple sclerosis may be more prone to fatal accidents than is the general population. To compare the rate of fatal accidents of Danish patients with MS with people in the general population, researchers collected data from the Danish MS Registry and the Cause of Death Registry. A total of 10,174 subjects who had   more »