Treosulfan (L-threitol-1,4-bis(methanesulfonate)) is a bifunctional alkylating agent with a favourable profile of side effects, approved for the treatment of ovarian cancer. Treosulfan has previously been shown to reduce the severity   more »

Type 1 diabetes mellitus (T1D) and multiple sclerosis (MS) contribute considerably to the burden of autoimmune diseases in young adults. Although HLA patterns of T1D and MS are considered mutually exclusive, individual and familial co-occurrence    more »

Conduction in a Demyelinated Nerve Fiber-KH

This slide shows abnormal conduction in a nerve fiber in demyelinating diseases.

Multiple sclerosis is not a single condition, but an ebbing and flowing of stages affecting the body’s central nervous system. Recognizing that pattern, researchers from the   more »

Objective: To examine the relation between low-contrast letter acuity, an emerging visual outcome for multiple sclerosis (MS) clinical trials, and   more »

For many people with MS, one of the early symptoms is a problem with vision. This may be in the form of temporary loss or blurring of vision, or double vision. Most people with MS who experience visual symptoms   more »

Although most hypersensitive reactions to natalizumab (Tysabri) occur within hours of the first dose, such responses may be delayed, according to   more »