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View Article  A Controlled Trial of Tysabri (Natalizumab) for Relapsing Multiple Sclerosis
The glycoprotein integrin is expressed on the surface of these cells and plays a critical part in their adhesion to the vascular endothelium and migration into the parenchyma. Tysabri (Natalizumab) is an integrin antagonist that reduced the development of brain lesions in   more »
View Article  Natural History of Multiple Sclerosis with Childhood Onset
We used data from 13 adult neurology departments affiliated with the European Database for Multiple Sclerosis (EDMUS) network to identify a cohort of 394 patients who had multiple sclerosis with an onset at 16 years of age or younger and a   more »
View Article  Fatigue Related To Depression Not Disability
Among some patients with multiple sclerosis, fatigue appears to persist over time but appears to be related to mood symptoms of depression and not to disability, a trial    more »
View Article  Natural history of secondary-progressive multiple sclerosis. (SPMS)
To examine prognosis and risk factors for progression to and from secondary-progressive multiple sclerosis (SPMS). Methods: Patients with definite relapsing-remitting MS (RRMS), onset before July 1988   more »