Relapse or worsening of depression. For most people, depression is a disease that will recur at least once — if not more frequently — after the first episode. Sometimes depression worsens for no apparent reason or due to added   more »

It's not clear precisely how SSRIs affect depression. Certain brain chemicals called neurotransmitters are associated with depression, including the neurotransmitter serotonin (ser-oh-   more »